I knew it when an elder got pregnant that it was all over. I tried killing her, but she didn't die, and she ignored my commands to go to the hospital, and had no interactions with anything or anyone. I tried force-reseting her- no dice.
Grape turned out a little better once he became an adult, but he's still pretty. Plantain looks pretty much like Kiwi and Carrot, so no surprise there.
It's been about a little over a year since I started making blends, and I STILL get giddy when I see my stuff in other people's games.