For the inaugural edition, I'm going with a classic from side 4 of Stevie Wonder's Songs in the Key of Life album. The song is "As". I was first introduced to this song via a mix CD a while back, and it probably was instrumental in turning me on to Wonder's music. It begins as a romantic ode with Stevie's amazingly clear voice, before descending into growls (as far as I can tell, that's still Stevie singing). Also, Herbie Hancock plays keyboards and provides hand claps.
It's a bit of a long one (7 minutes), so brace yourselves. Here's a link:
Stevie Wonder - As
(thanks to SeeqPod for help finding the mp3 online)